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RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription

All organisms—bacteria, archaea, and eukaryotes—have a transcription initiation factor that contains a structural module that binds within the RNA polymerase (RNAP) active-center cleft and interacts with template-strand single-stranded DNA (ssDNA) in the immediate vicinity of the RNAP active center....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Lingting, Molodtsov, Vadim, Lin, Wei, Ebright, Richard H., Zhang, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084136/
https://ncbi.nlm.nih.gov/pubmed/32127479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920747117
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