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The functional activity of E-cadherin controls tumor cell metastasis at multiple steps
E-cadherin is a tumor suppressor protein, and the loss of its expression in association with the epithelial mesenchymal transition (EMT) occurs frequently during tumor metastasis. However, many metastases continue to express E-cadherin, and a full EMT is not always necessary for metastasis; also, po...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7084067/ https://ncbi.nlm.nih.gov/pubmed/32127478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918167117 |
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