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p120-catenin phosphorylation status alters E-cadherin mediated cell adhesion and ability of tumor cells to metastasize

p120-catenin is considered to be a tumor suppressor because it stabilizes E-cadherin levels at the cell surface. p120-catenin phosphorylation is increased in several types of cancer, but the role of phosphorylation in cancer is unknown. The phosphorylation state of p120-catenin is important in contr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mendonsa, Alisha M., Bandyopadhyay, Chirosree, Gumbiner, Barry M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7319294/
https://ncbi.nlm.nih.gov/pubmed/32589661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235337
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