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Conformational epitopes at cadherin calcium-binding sites and p120-catenin phosphorylation regulate cell adhesion

We investigated changes in cadherin structure at the cell surface that regulate its adhesive activity. Colo 205 cells are nonadhesive cells with a full but inactive complement of E-cadherin–catenin complexes at the cell surface, but they can be triggered to adhere and form monolayers. We were able t...

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Detalhes bibliográficos
Main Authors: Petrova, Yuliya I., Spano, MarthaJoy M., Gumbiner, Barry M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364174/
https://ncbi.nlm.nih.gov/pubmed/22513089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-1060
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