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Enhanced endothelial barrier function by monoclonal antibody activation of vascular endothelial cadherin

Excessive vascular permeability occurs in inflammatory disease processes. Vascular endothelial cadherin (VE-cadherin) is an adhesion protein that controls vascular permeability. We identified monoclonal antibodies (mAbs) to human VE-cadherin that activate cell adhesion and inhibit the increased perm...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Park, Ki-Sook, Schecterson, Leslayann, Gumbiner, Barry M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8260392/
https://ncbi.nlm.nih.gov/pubmed/33577432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00002.2021
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