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Neddylated Cullin 3 is required for vascular endothelial‐cadherin‐mediated endothelial barrier function

Vascular endothelial (VE)‐cadherin, a major endothelial adhesion molecule, regulates vascular permeability, and increased vascular permeability has been observed in several cancers. The aim of this study was to elucidate the role of the NEDD8‐Cullin E3 ligase, in maintaining barrier permeability. To...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Sakaue, Tomohisa, Fujisaki, Ayako, Nakayama, Hironao, Maekawa, Masashi, Hiyoshi, Hiromi, Kubota, Eiji, Joh, Takashi, Izutani, Hironori, Higashiyama, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329144/
https://ncbi.nlm.nih.gov/pubmed/27987332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13133
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