Neddylated Cullin 3 is required for vascular endothelial‐cadherin‐mediated endothelial barrier function

Vascular endothelial (VE)‐cadherin, a major endothelial adhesion molecule, regulates vascular permeability, and increased vascular permeability has been observed in several cancers. The aim of this study was to elucidate the role of the NEDD8‐Cullin E3 ligase, in maintaining barrier permeability. To...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Sakaue, Tomohisa, Fujisaki, Ayako, Nakayama, Hironao, Maekawa, Masashi, Hiyoshi, Hiromi, Kubota, Eiji, Joh, Takashi, Izutani, Hironori, Higashiyama, Shigeki
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329144/
https://ncbi.nlm.nih.gov/pubmed/27987332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13133
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