Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection

Approaches to deplete persistent HIV infection are needed. We investigated the combined impact of the latency reversing agent vorinostat (VOR) and AGS-004, an autologous dendritic cell immunotherapeutic, on the HIV reservoir. HIV+, stably treated participants in whom resting CD4(+) T cell-associated...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Gay, Cynthia L., Kuruc, Joann D., Falcinelli, Shane D., Warren, Joanna A., Reifeis, Sarah A., Kirchherr, Jennifer L., James, Katherine S., Dewey, Morgan G., Helms, Alyson, Allard, Brigitte, Stuelke, Erin, Gamble, Alicia, Plachco, Ana, Gorelick, Robert J., Eron, Joseph J., Hudgens, Michael, Garrido, Carolina, Goonetilleke, Nilu, DeBenedette, Mark A., Tcherepanova, Irina Y., Nicolette, Charles A., Archin, Nancie M., Margolis, David M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083965/
https://ncbi.nlm.nih.gov/pubmed/32198428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61878-3
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