Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection

Approaches to deplete persistent HIV infection are needed. We investigated the combined impact of the latency reversing agent vorinostat (VOR) and AGS-004, an autologous dendritic cell immunotherapeutic, on the HIV reservoir. HIV+, stably treated participants in whom resting CD4(+) T cell-associated...

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Publicado no:Sci Rep
Main Authors: Gay, Cynthia L., Kuruc, Joann D., Falcinelli, Shane D., Warren, Joanna A., Reifeis, Sarah A., Kirchherr, Jennifer L., James, Katherine S., Dewey, Morgan G., Helms, Alyson, Allard, Brigitte, Stuelke, Erin, Gamble, Alicia, Plachco, Ana, Gorelick, Robert J., Eron, Joseph J., Hudgens, Michael, Garrido, Carolina, Goonetilleke, Nilu, DeBenedette, Mark A., Tcherepanova, Irina Y., Nicolette, Charles A., Archin, Nancie M., Margolis, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083965/
https://ncbi.nlm.nih.gov/pubmed/32198428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61878-3
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