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The role of fork stalling and DNA structures in causing chromosome fragility

Alternative non-B form DNA structures, also called secondary structures, can form in certain DNA sequences under conditions that produce single-stranded DNA, such as during replication, transcription, and repair. Direct links between secondary structure formation, replication fork stalling, and geno...

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Bibliographic Details
Published in:Genes Chromosomes Cancer
Main Authors: Kaushal, Simran, Freudenreich, Catherine H.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083089/
https://ncbi.nlm.nih.gov/pubmed/30536896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.22721
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