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PTEN Regulates DNA Replication Progression and Stalled Fork Recovery
Faithful DNA replication is a cornerstone of genomic integrity. PTEN plays multiple roles in genome protection and tumor suppression. Here we report on the importance of PTEN in DNA replication. PTEN depletion leads to impairment of replication progression and stalled fork recovery, indicating an el...
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| 發表在: | Nat Commun |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499867/ https://ncbi.nlm.nih.gov/pubmed/26158445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8620 |
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