RMI1 Promotes DNA Replication Fork Progression and Recovery from Replication Fork Stress

RMI1 is a member of an evolutionarily conserved complex composed of BLM and topoisomerase IIIα (TopoIIIα). This complex exhibits strand passage activity in vitro, which is likely important for DNA repair and DNA replication in vivo. The inactivation of RMI1 causes genome instability, including eleva...

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Bibliographic Details
Main Authors: Yang, Jay, O'Donnell, Lara, Durocher, Daniel, Brown, Grant W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434523/
https://ncbi.nlm.nih.gov/pubmed/22645306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00255-12
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