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RMI1 Promotes DNA Replication Fork Progression and Recovery from Replication Fork Stress

RMI1 is a member of an evolutionarily conserved complex composed of BLM and topoisomerase IIIα (TopoIIIα). This complex exhibits strand passage activity in vitro, which is likely important for DNA repair and DNA replication in vivo. The inactivation of RMI1 causes genome instability, including eleva...

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書目詳細資料
Main Authors: Yang, Jay, O'Donnell, Lara, Durocher, Daniel, Brown, Grant W.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434523/
https://ncbi.nlm.nih.gov/pubmed/22645306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00255-12
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