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MiRNA Targeting – Growing Beyond the Seed
MicroRNAs (miRNAs) are small RNAs that guide Argonaute (AGO) proteins to specific target messenger RNAs (mRNAs) to repress their translation and stability. Canonically, miRNA targeting is reliant on base pairing of the seed region, nucleotides (nts) 2–7, of the miRNA to sites in mRNA 3’UTRs. Recentl...
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| Udgivet i: | Trends Genet |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7083087/ https://ncbi.nlm.nih.gov/pubmed/30638669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2018.12.005 |
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