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About miRNAs, miRNA seeds, target genes and target pathways

miRNAs are typically repressing gene expression by binding to the 3’ UTR, leading to degradation of the mRNA. This process is dominated by the eight-base seed region of the miRNA. Further, miRNAs are known not only to target genes but also to target significant parts of pathways. A logical line of t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kehl, Tim, Backes, Christina, Kern, Fabian, Fehlmann, Tobias, Ludwig, Nicole, Meese, Eckart, Lenhof, Hans-Peter, Keller, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739805/
https://ncbi.nlm.nih.gov/pubmed/29291020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22363
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