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PI3K Inhibitors: Present and Future
Inhibitors of PI3Kδ hold great potential for the therapy of CLL and B cell malignancies. After initially exciting efficacy results with idelalisib, the first in class inhibitor, the emergence of unexpected and unpredictable autoimmune toxicities, worse in less heavily treated and younger patients, h...
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| 發表在: | Cancer J |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7082729/ https://ncbi.nlm.nih.gov/pubmed/31764120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000414 |
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