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PI3K Inhibitors: Present and Future

Inhibitors of PI3Kδ hold great potential for the therapy of CLL and B cell malignancies. After initially exciting efficacy results with idelalisib, the first in class inhibitor, the emergence of unexpected and unpredictable autoimmune toxicities, worse in less heavily treated and younger patients, h...

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Dades bibliogràfiques
Publicat a:Cancer J
Autor principal: Brown, Jennifer R.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082729/
https://ncbi.nlm.nih.gov/pubmed/31764120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000414
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