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PI3Kδ-Selective and PI3Kα/δ-Combinatorial Inhibitors in Clinical Development for B-Cell Non-Hodgkin Lymphoma

INTRODUCTION: Phosphatidylinositol-3-kinase (PI3K) inhibitors comprise a novel class of agents that are effective for the treatment of chronic lymphocytic leukemia (CLL) and indolent non-Hodgkin lymphoma (iNHL). The demonstrated efficacy and subsequent FDA approval of the prototypical PI3Kδ inhibito...

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Detaylı Bibliyografya
Yayımlandı:Expert Opin Investig Drugs
Asıl Yazarlar: Lampson, Benjamin L., Brown, Jennifer R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5747968/
https://ncbi.nlm.nih.gov/pubmed/28945111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13543784.2017.1384815
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