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PI3K Inhibitors: Present and Future

Inhibitors of PI3Kδ hold great potential for the therapy of CLL and B cell malignancies. After initially exciting efficacy results with idelalisib, the first in class inhibitor, the emergence of unexpected and unpredictable autoimmune toxicities, worse in less heavily treated and younger patients, h...

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Bibliografski detalji
Izdano u:Cancer J
Glavni autor: Brown, Jennifer R.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082729/
https://ncbi.nlm.nih.gov/pubmed/31764120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000414
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