In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against Mycobacterium tuberculosis

BACKGROUND AND PURPOSE: Tuberculosis has been reported to be the worldwide leading cause of death resulting from a sole infectious agent. The emergence of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis has made the battle against the infection more difficult since most...

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Bibliografiska uppgifter
I publikationen:Drug Des Devel Ther
Huvudupphovsmän: Venugopala, Katharigatta N, Tratrat, Christophe, Pillay, Melendhran, Chandrashekharappa, Sandeep, Al-Attraqchi, Omar Husham Ahmed, Aldhubiab, Bandar E, Attimarad, Mahesh, Alwassil, Osama I, Nair, Anroop B, Sreeharsha, Nagaraja, Venugopala, Rashmi, Morsy, Mohamed A, Haroun, Michelyne, Kumalo, Hezekiel M, Odhav, Bharti, Mlisana, Koleka
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove 2020
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082623/
https://ncbi.nlm.nih.gov/pubmed/32214795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S228381
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