Anti-Tubercular Activity of Substituted 7-Methyl and 7-Formylindolizines and In Silico Study for Prospective Molecular Target Identification

Novel series of diversely substituted indolizines were designed, synthesized, and evaluated for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) strains of Mycobacterium tuberculosis (MTB). Many compounds exhibited significant inhibitory activity against MTB H3...

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Bibliografski detalji
Izdano u:Antibiotics (Basel)
Glavni autori: Venugopala, Katharigatta N., Tratrat, Christophe, Pillay, Melendhran, Mahomoodally, Fawzi M., Bhandary, Subhrajyoti, Chopra, Deepak, Morsy, Mohamed A., Haroun, Michelyne, Aldhubiab, Bandar E., Attimarad, Mahesh, Nair, Anroop B., Sreeharsha, Nagaraja, Venugopala, Rashmi, Chandrashekharappa, Sandeep, Alwassil, Osama I., Odhav, Bharti
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963442/
https://ncbi.nlm.nih.gov/pubmed/31816928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics8040247
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