Anti-Tubercular Activity of Substituted 7-Methyl and 7-Formylindolizines and In Silico Study for Prospective Molecular Target Identification

Novel series of diversely substituted indolizines were designed, synthesized, and evaluated for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) strains of Mycobacterium tuberculosis (MTB). Many compounds exhibited significant inhibitory activity against MTB H3...

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Publicado no:Antibiotics (Basel)
Main Authors: Venugopala, Katharigatta N., Tratrat, Christophe, Pillay, Melendhran, Mahomoodally, Fawzi M., Bhandary, Subhrajyoti, Chopra, Deepak, Morsy, Mohamed A., Haroun, Michelyne, Aldhubiab, Bandar E., Attimarad, Mahesh, Nair, Anroop B., Sreeharsha, Nagaraja, Venugopala, Rashmi, Chandrashekharappa, Sandeep, Alwassil, Osama I., Odhav, Bharti
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963442/
https://ncbi.nlm.nih.gov/pubmed/31816928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics8040247
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