Augmenter of Liver Regeneration Protects Renal Tubular Epithelial Cells From Ischemia-Reperfusion Injury by Promoting PINK1/Parkin-Mediated Mitophagy

Ischemia–reperfusion (I/R) is the most common cause of acute kidney injury (AKI) and can induce apoptosis in renal epithelial tubule cells. Mitochondrial dysfunction is one of the main reasons for I/R-induced apoptosis. Accumulating evidence suggests that PINK1/Parkin-mediated mitophagy possibly pla...

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Publicat a:Front Physiol
Autors principals: Zhu, Dong-Ju, Liao, Xiao-Hui, Huang, Wen-Qi, Sun, Hang, Zhang, Ling, Liu, Qi
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7082309/
https://ncbi.nlm.nih.gov/pubmed/32231587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00178
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