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Albumin Overload and PINK1/Parkin Signaling-Related Mitophagy in Renal Tubular Epithelial Cells

BACKGROUND: Albumin, as a major urinary protein component, is a risk factor for chronic kidney disease progression. Mitochondrial dysfunction is one of the main causes of albumin-induced proximal tubule cells injury. Mitophagy is considered as a pivotal protective mechanism for the elimination of dy...

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Библиографические подробности
Опубликовано в: :Med Sci Monit
Главные авторы: Tan, Jin, Xie, Qi, Song, Shuling, Miao, Yuyang, Zhang, Qiang
Формат: Artigo
Язык:Inglês
Опубликовано: International Scientific Literature, Inc. 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843022/
https://ncbi.nlm.nih.gov/pubmed/29494565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.907718
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