Active Instrument Engagement Combined with a Real-Time Database Search for Improved Performance of Sample Multiplexing Workflows

Quantitative proteomics employing isobaric reagents has been established as a powerful tool for biological discovery. Current workflows often utilize a dedicated quantitative spectrum to improve quantitative accuracy and precision. A consequence of this approach is a dramatic reduction in the spectr...

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Pubblicato in:J Proteome Res
Autori principali: Erickson, Brian K., Mintseris, Julian, Schweppe, Devin K., Navarrete-Perea, José, Erickson, Alison R., Nusinow, David P., Paulo, Joao A., Gygi, Steven P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081948/
https://ncbi.nlm.nih.gov/pubmed/30658528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00899
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