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Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer
BACKGROUND: Prostate cancer changes the phenotype of cells within the stromal microenvironment, including fibroblasts, which in turn promote tumour progression. Functional changes in prostate cancer-associated fibroblasts (CAFs) coincide with alterations in DNA methylation levels at loci-specific re...
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| Publicado no: | Clin Epigenetics |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7081708/ https://ncbi.nlm.nih.gov/pubmed/32188493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00836-2 |
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