Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer

BACKGROUND: Prostate cancer changes the phenotype of cells within the stromal microenvironment, including fibroblasts, which in turn promote tumour progression. Functional changes in prostate cancer-associated fibroblasts (CAFs) coincide with alterations in DNA methylation levels at loci-specific re...

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Bibliografski detalji
Izdano u:Clin Epigenetics
Glavni autori: Lawrence, Mitchell G., Pidsley, Ruth, Niranjan, Birunthi, Papargiris, Melissa, Pereira, Brooke A., Richards, Michelle, Teng, Linda, Norden, Sam, Ryan, Andrew, Frydenberg, Mark, Stirzaker, Clare, Taylor, Renea A., Risbridger, Gail P., Clark, Susan J.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081708/
https://ncbi.nlm.nih.gov/pubmed/32188493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00836-2
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