Impaired bile acid metabolism with defectives of mitochondrial-tRNA taurine modification and bile acid taurine conjugation in the taurine depleted cats

Taurine that conjugates with bile acid (BA) and mitochondrial-tRNA (mt-tRNA) is a conditional essential amino acid in humans, similarly to cats. To better understand the influence of acquired depletion of taurine on BA metabolism, the profiling of BAs and its intermediates, BA metabolism-enzyme expr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Miyazaki, Teruo, Sasaki, Sei-Ich, Toyoda, Atsushi, Wei, Fan-Yan, Shirai, Mutsumi, Morishita, Yukio, Ikegami, Tadashi, Tomizawa, Kazuhito, Honda, Akira
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080809/
https://ncbi.nlm.nih.gov/pubmed/32188916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61821-6
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