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Impaired bile acid metabolism with defectives of mitochondrial-tRNA taurine modification and bile acid taurine conjugation in the taurine depleted cats

Taurine that conjugates with bile acid (BA) and mitochondrial-tRNA (mt-tRNA) is a conditional essential amino acid in humans, similarly to cats. To better understand the influence of acquired depletion of taurine on BA metabolism, the profiling of BAs and its intermediates, BA metabolism-enzyme expr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Miyazaki, Teruo, Sasaki, Sei-Ich, Toyoda, Atsushi, Wei, Fan-Yan, Shirai, Mutsumi, Morishita, Yukio, Ikegami, Tadashi, Tomizawa, Kazuhito, Honda, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080809/
https://ncbi.nlm.nih.gov/pubmed/32188916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61821-6
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