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Determination of Key Intermediates in Cholesterol and Bile Acid Biosynthesis by Stable Isotope Dilution Mass Spectrometry

For more than a decade, we have developed stable isotope dilution mass spectrometry methods to quantify key intermediates in cholesterol and bile acid biosynthesis, mevalonate and oxysterols, respectively. The methods are more sensitive and reproducible than conventional radioisotope (RI), gas-chrom...

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Autori principali: Yoshida, Tadashi, Honda, Akira, Miyazaki, Hiroshi, Matsuzaki, Yasushi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Libertas Academica 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701176/
https://ncbi.nlm.nih.gov/pubmed/19609389
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