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The COX-2/PGE(2) pathway suppresses apical elimination of RasV12-transformed cells from epithelia
At the initial stage of carcinogenesis, when RasV12-transformed cells are surrounded by normal epithelial cells, RasV12 cells are apically extruded from epithelia through cell competition with the surrounding normal cells. In this study, we demonstrate that expression of cyclooxygenase (COX)−2 is up...
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| Pubblicato in: | Commun Biol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7080752/ https://ncbi.nlm.nih.gov/pubmed/32188886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0847-y |
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