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Using backbone-cyclized Cys-rich polypeptides as molecular scaffolds to target protein-protein interactions

The use of disulfide-rich backbone cyclized polypeptides as molecular scaffolds to design a new generation of bioimaging tools and drugs that are potent and specific, and thus might have fewer side effects than traditional small molecule drugs is gaining increasing interest among the scientific but...

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Bibliografiske detaljer
Udgivet i:Biochem J
Main Authors: Chaudhuri, Dipankar, Aboye, Teshome, Camarero, Julio A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080216/
https://ncbi.nlm.nih.gov/pubmed/30635453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180792
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