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Using backbone-cyclized Cys-rich polypeptides as molecular scaffolds to target protein-protein interactions

The use of disulfide-rich backbone cyclized polypeptides as molecular scaffolds to design a new generation of bioimaging tools and drugs that are potent and specific, and thus might have fewer side effects than traditional small molecule drugs is gaining increasing interest among the scientific but...

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Detalles Bibliográficos
Publicado en:Biochem J
Main Authors: Chaudhuri, Dipankar, Aboye, Teshome, Camarero, Julio A.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7080216/
https://ncbi.nlm.nih.gov/pubmed/30635453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180792
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