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Changing the topology of protein backbone: the effect of backbone cyclization on the structure and dynamics of a SH3 domain

Understanding of the effects of the backbone cyclization on the structure and dynamics of a protein is essential for using protein topology engineering to alter protein stability and function. Here we have determined, for the first time, the structure and dynamics of the linear and various circular...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Chem
Egile Nagusiak: Schumann, Frank H., Varadan, Ranjani, Tayakuniyil, Praveen P., Grossman, Jennifer H., Camarero, Julio A., Fushman, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389572/
https://ncbi.nlm.nih.gov/pubmed/25905098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2015.00026
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