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Biosynthesis and antimicrobial evaluation of backbone-cyclized alpha-defensins(#)

Defensins are antimicrobial peptides that are important in the innate immune defense of mammals. Upon stimulation by bacterial antigens, enteric α-defensins are secreted into the intestinal lumen where they have potent microbicidal activities. Cryptdin-4 (Crp4) is an α-defensin expressed in Paneth c...

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Detalhes bibliográficos
Main Authors: Garcia, Angie E., Tai, Kenneth P., Puttamadappa, Shadakshara S., Shekhtman, Alexander, Ouellette, Andre J., Camarero, Julio A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236816/
https://ncbi.nlm.nih.gov/pubmed/22040603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201430f
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