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Biosynthesis and antimicrobial evaluation of backbone-cyclized alpha-defensins(#)
Defensins are antimicrobial peptides that are important in the innate immune defense of mammals. Upon stimulation by bacterial antigens, enteric α-defensins are secreted into the intestinal lumen where they have potent microbicidal activities. Cryptdin-4 (Crp4) is an α-defensin expressed in Paneth c...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3236816/ https://ncbi.nlm.nih.gov/pubmed/22040603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201430f |
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