Cargando...

Efficient one-pot cyclization/folding of Rhesus θ-defensin-1 (RTD-1)

We report an efficient approach for the chemical synthesis of Rhesus θ-defensin-1 (RTD-1) using Fmoc-based solid-phase peptide synthesis in combination with an intramolecular version of native chemical ligation. The corresponding linear thioester precursor was cyclized and folded in a one-pot reacti...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Aboye, Teshome L., Li, Yilong, Majumder, Subhabrata, Hao, Jinfeng, Shekhtman, Alexander, Camarero, Julio A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590006/
https://ncbi.nlm.nih.gov/pubmed/22425570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.02.080
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!