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Cyclotides, a novel ultrastable polypeptide scaffold for drug discovery

Cyclotides are a unique and growing family of backbone cyclized peptides that also contain a cystine knot motif built from six conserved cysteine residues. This unique circular backbone topology and knotted arrangement of three disulfide bonds makes them exceptionally stable to thermal, chemical, an...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gould, Andrew, Ji, Yanbin, Aboye, Teshome L., Camarero, Julio A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330703/
https://ncbi.nlm.nih.gov/pubmed/22204428
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