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The Potential of the Cyclotide Scaffold for Drug Development
Cyclotides are a novel class of micro-proteins (≈30–40 residues long) with a unique topology containing a head-to-tail cyclized backbone structure further stabilized by three disulfide bonds that form a cystine knot. This unique molecular framework makes them exceptionally stable to physical, chemic...
Enregistré dans:
| Publié dans: | Biomedicines |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6631875/ https://ncbi.nlm.nih.gov/pubmed/31010257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines7020031 |
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