Characterization of two in vivo challenge models to measure functional activity of monoclonal antibodies to Plasmodium falciparum circumsporozoite protein

BACKGROUND: New strategies are needed to reduce the incidence of malaria, and promising approaches include the development of vaccines and monoclonal antibodies (mAbs) that target the circumsporozoite protein (CSP). To select the best candidates and speed development, it is essential to standardize...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Raghunandan, Rama, Mayer, Bryan T., Flores-Garcia, Yevel, Gerber, Monica W., Gottardo, Raphael, Jhun, Hugo, Herrera, Sonia M., Perez-Ramos, Daniel W., Locke, Emily, King, C. Richter, Zavala, Fidel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079517/
https://ncbi.nlm.nih.gov/pubmed/32183833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03181-0
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