Cerebrospinal Fluid Characterization in Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs

Intrathecal administration is an important route for drug delivery, and in pharmacology and toxicology studies, cerebrospinal fluid (CSF) collection and analysis is required for evaluating blood–brain barrier penetration and central nervous system exposure. The characteristics of CSF in commonly use...

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Vydáno v:Int J Toxicol
Hlavní autoři: Ballesteros, Cristina, Pouliot, Mylène, Froment, Rémi, Maghezzi, Mohamed Said, St-Jean, Camille, Li, Christian, Paquette, Dominique, Authier, Simon
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2020
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079291/
https://ncbi.nlm.nih.gov/pubmed/32066300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1091581820905092
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