A minimally-invasive serial cerebrospinal fluid sampling model in conscious Göttingen minipigs

Drug concentrations in cerebrospinal fluid (CSF) are typically used as a as a surrogate measure of their availability in the CNS, and CSF penetration in animal studies are used for assessment of CNS drug delivery in early preclinical drug development. The minipig is a valid alternative to dogs and n...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Methods
Egile Nagusiak: Bergadano, Alessandra, Amen, Eva Maria, Jacobsen, Björn, Belli, Sara, Vandjour, Anthony, Rapp, Christelle, Senn, Claudia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Journal of Biological Methods 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6706129/
https://ncbi.nlm.nih.gov/pubmed/31453257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14440/jbm.2019.265
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak