Cerebrospinal Fluid Characterization in Cynomolgus Monkeys, Beagle Dogs, and Göttingen Minipigs

Intrathecal administration is an important route for drug delivery, and in pharmacology and toxicology studies, cerebrospinal fluid (CSF) collection and analysis is required for evaluating blood–brain barrier penetration and central nervous system exposure. The characteristics of CSF in commonly use...

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Bibliographic Details
Published in:Int J Toxicol
Main Authors: Ballesteros, Cristina, Pouliot, Mylène, Froment, Rémi, Maghezzi, Mohamed Said, St-Jean, Camille, Li, Christian, Paquette, Dominique, Authier, Simon
Format: Artigo
Language:Inglês
Published: SAGE Publications 2020
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079291/
https://ncbi.nlm.nih.gov/pubmed/32066300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1091581820905092
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