Alum impairs tolerogenic properties induced by allergoid‐mannan conjugates inhibiting mTOR and metabolic reprogramming in human DCs

BACKGROUND: Polymerized allergoids conjugated to mannan (PM) are suitable vaccines for allergen‐specific immunotherapy (AIT). Alum remains the most widely used adjuvant in AIT, but its way of action is not completely elucidated. The better understanding of the mechanisms underlying alum adjuvanticit...

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Detaylı Bibliyografya
Yayımlandı:Allergy
Asıl Yazarlar: Benito‐Villalvilla, Cristina, Soria, Irene, Pérez‐Diego, Mario, Fernández‐Caldas, Enrique, Subiza, José Luis, Palomares, Oscar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
ORIGINAL ARTICLES
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079174/
https://ncbi.nlm.nih.gov/pubmed/31494959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14036
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