Alum impairs tolerogenic properties induced by allergoid‐mannan conjugates inhibiting mTOR and metabolic reprogramming in human DCs

BACKGROUND: Polymerized allergoids conjugated to mannan (PM) are suitable vaccines for allergen‐specific immunotherapy (AIT). Alum remains the most widely used adjuvant in AIT, but its way of action is not completely elucidated. The better understanding of the mechanisms underlying alum adjuvanticit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Allergy
Hauptverfasser: Benito‐Villalvilla, Cristina, Soria, Irene, Pérez‐Diego, Mario, Fernández‐Caldas, Enrique, Subiza, José Luis, Palomares, Oscar
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
ORIGINAL ARTICLES
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7079174/
https://ncbi.nlm.nih.gov/pubmed/31494959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14036
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge