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Oxidative stress‐alleviating strategies to improve recombinant protein production in CHO cells
Large scale biopharmaceutical production of biologics relies on the overexpression of foreign proteins by cells cultivated in stirred tank bioreactors. It is well recognized and documented fact that protein overexpression may impact host cell metabolism and that factors associated with large scale c...
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| Udgivet i: | Biotechnol Bioeng |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7078918/ https://ncbi.nlm.nih.gov/pubmed/31814104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27247 |
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