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Oxidative stress‐alleviating strategies to improve recombinant protein production in CHO cells

Large scale biopharmaceutical production of biologics relies on the overexpression of foreign proteins by cells cultivated in stirred tank bioreactors. It is well recognized and documented fact that protein overexpression may impact host cell metabolism and that factors associated with large scale c...

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Detaylı Bibliyografya
Yayımlandı:Biotechnol Bioeng
Asıl Yazarlar: Chevallier, Valentine, Andersen, Mikael Rørdam, Malphettes, Laetitia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7078918/
https://ncbi.nlm.nih.gov/pubmed/31814104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27247
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