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Optimizing Recombinant Protein Production in the Escherichia coli Periplasm Alleviates Stress

In Escherichia coli, many recombinant proteins are produced in the periplasm. To direct these proteins to this compartment, they are equipped with an N-terminal signal sequence so that they can traverse the cytoplasmic membrane via the protein-conducting Sec translocon. Recently, using the single-ch...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Baumgarten, Thomas, Ytterberg, A. Jimmy, Zubarev, Roman A., de Gier, Jan-Willem
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981079/
https://ncbi.nlm.nih.gov/pubmed/29654183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00270-18
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