Escherichia coli Can Adapt Its Protein Translocation Machinery for Enhanced Periplasmic Recombinant Protein Production

Recently, we engineered a tunable rhamnose promoter-based setup for the production of recombinant proteins in E. coli. This setup enabled us to show that being able to precisely set the production rate of a secretory recombinant protein is critical to enhance protein production yields in the peripla...

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Bibliografske podrobnosti
izdano v:Front Bioeng Biotechnol
Main Authors: Karyolaimos, Alexandros, Dolata, Katarzyna Magdalena, Antelo-Varela, Minia, Mestre Borras, Anna, Elfageih, Rageia, Sievers, Susanne, Becher, Dörte, Riedel, Katharina, de Gier, Jan-Willem
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Bioengineering and Biotechnology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000420/
https://ncbi.nlm.nih.gov/pubmed/32064253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00465
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