LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes

OBJECTIVES: The concept of trained innate immunity describes a long-term proinflammatory memory in innate immune cells. Trained innate immunity is regulated through reprogramming of cellular metabolic pathways including cholesterol and fatty acid synthesis. Here, we have analyzed the role of Liver X...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Sohrabi, Yahya, Sonntag, Glenn V. H., Braun, Laura C., Lagache, Sina M. M., Liebmann, Marie, Klotz, Luisa, Godfrey, Rinesh, Kahles, Florian, Waltenberger, Johannes, Findeisen, Hannes M.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077358/
https://ncbi.nlm.nih.gov/pubmed/32210962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00353
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