LXR Activation Induces a Proinflammatory Trained Innate Immunity-Phenotype in Human Monocytes

OBJECTIVES: The concept of trained innate immunity describes a long-term proinflammatory memory in innate immune cells. Trained innate immunity is regulated through reprogramming of cellular metabolic pathways including cholesterol and fatty acid synthesis. Here, we have analyzed the role of Liver X...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Sohrabi, Yahya, Sonntag, Glenn V. H., Braun, Laura C., Lagache, Sina M. M., Liebmann, Marie, Klotz, Luisa, Godfrey, Rinesh, Kahles, Florian, Waltenberger, Johannes, Findeisen, Hannes M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077358/
https://ncbi.nlm.nih.gov/pubmed/32210962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00353
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