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mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes

Introduction: Cells of the innate immune system particularly monocytes and macrophages have been recognized as pivotal players both during the initial insult as well as the chronic phase of atherosclerosis. It has recently been shown that oxidized low-density lipoprotein (oxLDL) induces a long-term...

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Autori principali: Yahya Sohrabi, Sina M. M. Lagache, Lucia Schnack, Rinesh Godfrey, Florian Kahles, Dennis Bruemmer, Johannes Waltenberger, Hannes M. Findeisen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019-01-01
Serie:Frontiers in Immunology
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Accesso online:https://www.frontiersin.org/article/10.3389/fimmu.2018.03155/full
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