Rapid Progression from Mild Cognitive Impairment to Alzheimer's Disease in Subjects with Elevated Levels of Tau in Cerebrospinal Fluid and the APOE ε4/ε4 Genotype

BACKGROUND/AIMS: Increased cerebrospinal fluid (CSF) tau, decreased CSF amyloid-β42 (Aβ42) and the apolipoprotein E gene (APOE) ε4 allele predict progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD). Here, we investigated these markers to assess their predictive value an...

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Publicado en:Dement Geriatr Cogn Disord
Autores principales: Blom, Elin S., Giedraitis, Vilmantas, Zetterberg, Henrik, Fukumoto, Hiroaki, Blennow, Kaj, Hyman, Bradley T., Irizarry, Michael C., Wahlund, Lars-Olof, Lannfelt, Lars, Ingelsson, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2009
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Original Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077080/
https://ncbi.nlm.nih.gov/pubmed/19420940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000216841
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