Insulin resistance is associated with higher cerebrospinal fluid tau levels in asymptomatic APOE ε4 carriers

BACKGROUND: Insulin resistance (IR) is linked with the occurrence of pathological features observed in Alzheimer's disease (AD), including neurofibrillary tangles and amyloid plaques. However, the extent to which IR is associated with AD pathology in the cognitively asymptomatic stages of precl...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Starks, Erika J., O'Grady, J. Patrick, Hoscheidt, Siobhan M., Racine, Annie M., Carlsson, Cindy M., Zetterberg, Henrik, Blennow, Kaj, Okonkwo, Ozioma C., Puglielli, Luigi, Asthana, Sanjay, Dowling, N. Maritza, Gleason, Carey E., Anderson, Rozalyn M., Davenport-Sis, Nancy J., DeRungs, LeAnn M., Sager, Mark A., Johnson, Sterling C., Bendlin, Barbara B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583335/
https://ncbi.nlm.nih.gov/pubmed/25812851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150072
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